Case Western Reserve University School of Medicine, USA

Immunology

Vaccinogen Inc., USA

cancer vaccines

Heather Medbury is a Senior Research Fellow at the University of Sydney, and is based at Westmead Hospital. She completed her PhD in transplant immunology before transferring to Vascular Biology to work for Professor John Fletcher, the head of Surgery for the University. Heather established laboratory based research for the Department of Surgery at Westmead Hospital which, combined with the large animal work operating in the Department, become known as the Vascular Biology Research Centre. Her work has received oral presentations at national and international meetings including at the American Heart Association (2004) and International Atherosclerosis Society meetings

Our research focus is cardiovascular disease. It is not just a global problem, but likely a personal one, as it doesn't just happen in someone else's family, but often within your own. Despite current treatments, patients with cardiovascular disease have a considerable residual risk of experiencing a clinical event (such as a heart attack or stroke). A challenge now is to develop strategies to prevent these remaining cardiovascular events. Though inflammation is thought to be a key contributor to residual risk, it is not a current treatment target. For the benefit of anti-inflammatory treatments to outweigh the risks, specific approaches will be required. A potential treatment target is the monocyte, as monocyte derived cells play a key role atherosclerotic plaque development and progression. Thus the focus of our group is to redefine the role of monocytes and macrophages in atherosclerosis in order to identify targets for therapeutic manipulation that could stabilize the disease. This will potentially result in a reduction in events such as heart attack and stroke that will not only decrease the morbidity and mortality associated with the disease, but also limit the associated, health, social and economic burdens it poses.

Noah Isakov is a Professor of Immunology and Chair of The Shraga Segal Department of Microbiology and Immunology at the Faculty of Health Sciences Ben Gurion University of the Negev Beer Sheva Israel. He received his PhD from the Weizmann Institute of Science in Rehovot Israel 1981 and performed postdoctoral studies at the University of Minnesota in Minneapolis MN 1981-1983 and the Scripps Research Institute in La Jolla CA 1983-1987. He performed a Sabbatical at the National Institute of Allergy and Infectious Diseases at the NIH Bethesda MD 1993-1995 and served as an Esther Z Greenberg Honors Chair in Biomedical Research at the Oklahoma Medical Research Foundation in Oklahoma City OK 2003-2004 and President of the Israel Immunological Society 2004-2006.

The general aim of our laboratory is to decipher signal transduction mechanisms that regulate T lymphocyte activation, function and differentiation into effector cells, as well as the characterisation of proto-oncogen products that are involved in cell transformation.

Kaihong Su is currently working as an Associate Professor in the Department of Pathology and Microbiology, College of medicine at University of Nebraska. Her research focuses on basic and translational research on autoimmune diseases. The ultimate goal is to understand the disease pathogenesis and identify novel biomarkers and pathways that can be developed into diagnostic/therapeutic tools for these diseases. She has completed her B.S., Nankai University (Microbiology), P. R. China, 1990 & M.S., from Nankai University (Microbiology), P. R. China in 1993. Ph.D., from University of Alabama at Birmingham (Cell Biology), Alabama, in 1998 & Post-doctoral training (Immunology) from University of Alabama at Birmingham, Alabama from 1998-2002

Immunology autoimmune diseases autoantibodies and neutrophils Research Interest

Ahmed Hegazi (or Ahmed Gaffer Hegazi; احمد جعفر حجازى) (born May 31, 1948) is currently a Professor of Microbiology and Immunology in the department of Zoonotic Diseases, National Research Center, Egypt. Prof. Hegazi received his masters degree in 1979, and his PhD in 1981. Hegazi's research work has been focused lately on bee products and their therapeutic effects. Hegazi Organized and contributed to national and international research projects since 1977 and up till now; he has been the principal investigator on multiple research projects within the National Research Center. He has published 166 scientific papers and articles in national and international journals. He also served on the board of multiple national and international scientific journals. Dr. Hegazi is also the president of the Egyptian Environmental Society for Uses and Production of Bee Products, secretary of the Egyptian Society of Apitherapy, secretary general of the African Federation of Apiculture Associations, and a member of the International Apitherapy Commission (APIMONDIA). Awards First Class Decoration of Excellence, Egypt, 1995 The Senior Scientist Prize of National Research Center, Cairo, Egypt, 1996 The National Scientific Prize In Biological Sciences, Egypt, 1990 The Scientific Prize of The National Research Center, Cairo, Egypt, 1989 The Second Best Research Paper Award, International Congress of Propolis, Bones Airs, Argentina, 2000 Main Speaker Award,10th Academic Conference, PRA and NAS (Nippon Apitherapy Soc.) Japan, 2006 2 Bronze medals from The International Innovation Fair of the Middle East, Kuwait, 2007 Patents Patent No. 8901 at 22/08/2006: A novel drug from natural products with new therapeutic modalities in treatment of psoriasis Patent No. 1005 at 02/01/2006: A novel drug from natural resources for controlling Fascioliasis Patent No. 270: at 01/06/2005: A novel drug from medicinal plants with antiatherosclerotic (hypocholesterolaemic), antioxidant and cardio protective properties. Patent No. 272: at 01/06/2005: A novel drug from natural resources with antiatherosclerotic (hypocholesterolaemic), antioxidant and cardio protective properties. Scientific Activities Editor in the following International Journals: Research Journal of Allergy, 2007 International Journal of Virology, 2007 Current Research In Tuberculosis, 2007 Research Journal of Veterinary Science, 2007 Research Journal of Microbiology, 2007 International Journal of Cancer Research, 2007 Research Journal of Medicinal plants, 2007 Referee in the following International Journals: Journal of Planta Medica, 2005 Journal of Evidence Based Complementary and Alternative Medicine, 2006 International Journal of Radiation Biology, 2007

Apitherapy, Immunology

Dr. Ian Martins has been invited to join the Editors of various international journals and has been a reviewer for various journals (approx. 40). He was appointed as the Chief Editor for International Journal of Diabetes Research (2014-2017). He is a BIT Member (BIT Congress. Inc) with an H-index of 42, (ResearchGate STATs (22), Mendeley STATS (20). The total citations over the past 27 years has accumulated to 2830. ResearchGate’s analysis available on google, Tweet, Facebook, Lindekin under Ian James Martins’ name places Dr Martins’ publication stats RG score higher than 96% of the international researchers and is now a SCIENTIST (ResearchGate). Dr Martins has received certificates of recognition at various conferences/congresses in relation to anti-aging medicine. Prevention of over eating by food restriction improves the peripheral sink hepatic abeta clearance relevant to liver lipid metabolism important to improving health and global chronic diseases.

Ethnopharmacology, Pharmacology

Dr. Mohamed Jahromi is currently working at Department of Pathology, Salmaniya Medical Complex, Bahrain. His research interest is based on Molecular Biology, Genetics, Biochemistry, Immunology, Cancer Biology, PCR, Western Blot, ELISA. He has published many articles in reputed journals.

Molecular Biology, Genetics, Biochemistry, Immunology, Cancer Biology, PCR, Western Blot, ELISA

Professor Tadamitsu Kishimoto is a world-renowned immunologist who was born in 1939 Osaka, Japan. After graduating from Osaka University Medical School in 1964, he completed a one-year internship at Osaka University Hospital, followed by Ph.D. studies in medicine from 1965 to 1969. Between 1970 and 1974, he pursued post-doctoral research in the Department of Medicine at Johns Hopkins Medical School, working under Professor Kimishige Ishizaka, the discoverer of IgE. He returned to Osaka University Medical School in Professor-Tadamitsu-Kishimoto1974 as assistant professor of medicine and progressed rapidly through his academic and research career becoming professor in 1979. He has served as dean and chairman of the Department of Medicine at Osaka University and was the university’s president from 1997-2003 and a Member of the Council for Science and Technology Policy from 2004 to 2006. Currently, he is professor of Immunology at the Immunology Frontier Research Center in Osaka University.

Post-transcriptional regulation of IL-6 has been largely uncharacterized, with the exception of the RNase Regnase-1, which prevents autoimmunity by destabilizing IL-6 mRNA

Current research projects are focused in study the complex relationships between the host and the microbiota and understand the foundations of innate immunity at a stage in which ZF larva rely 100% on it. For this porpoise we use germ-free or conventionally raised wild type or transgenic fish expressing fluorescent proteins under the control of specific promoters that further-on would be analyzed through live-imaging and molecular techniques, mainly qPCR.

raised wild type or transgenic fish expressing fluorescent proteins under the control of specific promoters that further-on would be analyzed through live-imaging and molecular techniques, mainly qPCR.

Veronica trained in medicine at St Mary’s Hospital, London. She has 3 certificates of specialist training (general medicine, respiratory medicine and clinical immunology and allergy). She has been a consultant at St Helier Hospital, Carshalton, Surrey since 1996. She was a Senior Registrar at Southampton General Hospital for 3 years, a Registrar at Royal Brompton Hospital for 3 years and at Papworth and Addenbrooks Hospital Cambridge for 2 years. Her research interests are Pulmonary fibrosis, Asthma and Anaphylaxis.

Her research interests are Pulmonary fibrosis, Asthma and Anaphylaxis. , General medicine, respiratory medicine and clinical immunology and allergy

Maulin P. Shah, currently Head and Senior Manager – Industrial Waste Water Research Lab, Division of Applied and Environmental Microbiology Lab at Enviro Technology Ltd., Ankleshwar, Gujarat, India, received his Ph.D. (2002-2005) in Environmental Microbiology from Sardar Patel University, Vallabh Vidyanagar, Gujarat. He has served as an Assistant Professor at Godhra, Gujarat University in 2001. He is a Microbial Biotechnologist with diverse research interest. A group of research scholars is working under his guidance on the areas ranging from Applied Microbiology, Environmental Biotechnology, Bioremediation, and Industrial Liquid Waste Management to solid state fermentation. His work has been focused to assess the impact of industrial pollution on microbial diversity of wastewater following cultivation dependant and cultivation independent analysis. His major work involves isolation, screening, identification and Genetic Engineering of high impact of Microbes for the degradation of hazardous materials. He has more than 140 research publication in highly reputed national and international journals. He directs the Research program at Enviro Technology Ltd., Ankleshwar. He has guided more than 20 Post Graduate students in various disciplines of Life Science. He extends his expertise in various National as well as International Reputed Journal as Editor and Editorial Board Member like Open Access Book of Cloud Publication, Journal of Environment Pollution and Human Health. He was Founder Editor-in-Chief of International Journal of Environmental Bioremediation and Biodegradation (2012-2014) as well as Journal of Applied and Environmental Microbiology (2012-2014) (Science and Education Publishing, USA), Editorial Board Member of American Journal of Microbiological Research, Electronic Journal of Energy and Environment, International Journal of Environment and Sustainability. He is also serving as a reviewer in various journals of national and international repute. Recently, he has been appointed as a Reviewer in Nature Biotechnology Journal.

Environmental Microbiology, Bio-remediation, Bio-degradation, Industrial Waste Water Treatment, Applied Microbiology, Enzyme Engineering, Liquid to Solid State Fermentation, Waste Water Genomics

Gregory Lee received his Ph. D from the California Institute of Technology and completed his postdoctoral studies at the University of California, San Diego. He became a full Professor at the University of British Columbia in 1989, and retired in 2012 with the title of Professor Emeritus. He is the co-founder of Vancouver Biotech Ltd. He has published more than 200 papers, including 30 papers in cancer research. He has been serving as an editorial board member of the Journal of Carcinogenesis and Mutagenesis, and the Journal of Cancer Science and Therapy since 2012.

Antigen receptors, including immunoglobulins and T-cell receptors

Charles J Malemud received the PhD from George Washington University in 1973 and completed postdoctoral studies at the State University of New York at Stony Brook in 1977. He is Professor of Medicine & Anatomy in the Division of Rheumatic Diseases and Senior Investigator in the Arthritis Research Laboratory at Case Western Reserve University School of Medicine. He has published more than 200 papers and reviews primarily in the field of chondrocyte biology. He is on the editorial board of several rheumatology, immunology and musculoskeletal journals and is Editor-in-Chief of the Journal of Clinical and Cellular Immunology.

Biology of the Musculoskeletal System Intracellular Signal Transduction Pathways Inflammation Pro-inflammatory, Anti-Inflammatory & Anabolic Cytokines Apoptosis Matrix metalloproteinases Osteoarthritis Rheumatoid Arthritis Fibromyalgia Autoimmune Disorders Research Interest

Sudhir Gupta is a Professor of Medicine, Pathology & Laboratory Medicine, and Microbiology & Molecular Genetics, Chief of the Division of Basic and Clinical Immunology, and the Director of the Jeffrey Modell Diagnostic Center in Primary Immunodeficiencies at the University of California, Irvine. He also serves as Director of Scientific Development at the Sass Foundation for Medical Research in New York. Dr Gupta received his medical and doctorate degrees from the King George's Medical College in Lucknow, India. Previous appointments include Associate Professor of Medicine and Immunology at the Weill Cornell Medical College, and Associate Member at the Sloan-Kettering Institute for Cancer Research, both in New York, New York. Dr Gupta is board certified in Clinical Immunology by the Royal College of Physicians and Surgeons of Canada; he is board certified in Allergy and Immunology, and Diagnostic Laboratory Immunology by the American Board of Allergy and Immunology. Dr Gupta is a Master of the American College of Physicians. Dr. Gupta has served on a number of committees for many leading governmental bodies and organizations, including the National Institutes of Health, the U.S. Food and Drug Administration, and the World Health Organization. Dr Gupta has made many original contributions in the field of cellular and molecular immunology as it relates to primary immunodeficiency diseases, AIDS, cancer research, and aging. These findings have been published in high-impact journals, including Science, Nature, the Proceedings of the National Academy of Sciences, the Journal of Experimental Medicine, the Journal of Clinical Investigation, the New England Journal of Medicine, and Aging Cell. Dr Gupta has published more than 500 scientific papers, invited reviews, and book chapters. He has edited 24 books in various areas of cellular, molecular, and applied immunology, including one on primary immunodeficiency.

Molecular signaling of apoptosis, Dendritic cell biology, B cell biology, Genetic basis of primary immunodeficiency diseases

Michael Tainsky is a molecular cell biologist who has been studying the molecular basis of human cancer for more than 30 years. In 1998, he came to the Karmanos Cancer Institute at Wayne State University School of Medicine after 13 years on the faculty of the University of Texas, M.D. Anderson Cancer Center in Houston, TX, and 8 years at NCI/NIH. He has studied the biological effects of oncogenes, tumor suppressor genes, and transcription factor on tumor cells; and in the Li-Fraumeni Cancer Syndrome, he studied the mechanisms of cellular immortalization. Recently, he extended his mechanistic cancer research to translational applications of genomics and proteomics to molecular diagnostics of ovarian cancer. For the past 10 years, his laboratory team has developed the epitope cloning technology and protein microarray immunoassays to detect tumor autoantibodies in patients’ sera. His Epitomics Biomarker Technology identifies the autoantigen biomarkers using novel informatics tools for the classification of patients. In 2009, he published a 330-page book as editor in the Methods in Molecular Biology Series from Humana Press entitled Tumor Biomarker Discovery. He was invited to guest edit Special Issues of the journal Cancer Biomarkers on Antibody Biomarkers and Biomarkers in Ovarian Cancer. Dr. Tainsky holds the Barbara and Fred Erb Chair in Cancer Genetics at the Barbara Ann Karmanos Cancer Institute. He is a professor in the Department of Oncology.

• Molecular genetic mechanisms by which normal cells become malignant • Pathway analysis of gene expression changes leading to cellular immortalization • Development of novel cancer diagnostic tests for early detection of cancer in the form of a complex blood test

Martin D’Souza has completed his PhD from the University of Pittsburgh, PA. He is the director of Graduate Programs at Mercer University, College of Pharmacy and Co-Director of the Center for Drug Delivery. He has published more than 80 manuscripts and is on the editorial board of several journals.

The D'Souza nanotechnology laboratory mainly focuses on the design of novel patented technologies to deliver nano vaccines via the oral, buccal, parenteral and microneedle based transdermal route. Examples include: viral vaccines such as influenza vaccines, HIV and human papilloma vaccines (HPV); bacterial vaccines such as pneumonia, meningitis, TB and typhoid; and cancer vaccines, such as breast, melanoma, prostate, liver and ovarian. Recently, we also have been involved in tissue bio-engineering- applications including the use of cell encapsulation and thermo-sensitive gels for transplantation of pancreatic cells in diabetes.

Ahmed Hegazi (or Ahmed Gaffer Hegazi; احمد جعفر حجازى) (born May 31, 1948) is currently a Professor of Microbiology and Immunology in the department of Zoonotic Diseases, National Research Center, Egypt. Prof. Hegazi received his masters degree in 1979, and his PhD in 1981. Hegazi's research work has been focused lately on bee products and their therapeutic effects. Hegazi Organized and contributed to national and international research projects since 1977 and up till now; he has been the principal investigator on multiple research projects within the National Research Center. He has published 166 scientific papers and articles in national and international journals. He also served on the board of multiple national and international scientific journals. Dr. Hegazi is also the president of the Egyptian Environmental Society for Uses and Production of Bee Products, secretary of the Egyptian Society of Apitherapy, secretary general of the African Federation of Apiculture Associations, and a member of the International Apitherapy Commission (APIMONDIA). Awards First Class Decoration of Excellence, Egypt, 1995 The Senior Scientist Prize of National Research Center, Cairo, Egypt, 1996 The National Scientific Prize In Biological Sciences, Egypt, 1990 The Scientific Prize of The National Research Center, Cairo, Egypt, 1989 The Second Best Research Paper Award, International Congress of Propolis, Bones Airs, Argentina, 2000 Main Speaker Award,10th Academic Conference, PRA and NAS (Nippon Apitherapy Soc.) Japan, 2006 2 Bronze medals from The International Innovation Fair of the Middle East, Kuwait, 2007 Patents Patent No. 8901 at 22/08/2006: A novel drug from natural products with new therapeutic modalities in treatment of psoriasis Patent No. 1005 at 02/01/2006: A novel drug from natural resources for controlling Fascioliasis Patent No. 270: at 01/06/2005: A novel drug from medicinal plants with antiatherosclerotic (hypocholesterolaemic), antioxidant and cardio protective properties. Patent No. 272: at 01/06/2005: A novel drug from natural resources with antiatherosclerotic (hypocholesterolaemic), antioxidant and cardio protective properties. Scientific Activities Editor in the following International Journals: Research Journal of Allergy, 2007 International Journal of Virology, 2007 Current Research In Tuberculosis, 2007 Research Journal of Veterinary Science, 2007 Research Journal of Microbiology, 2007 International Journal of Cancer Research, 2007 Research Journal of Medicinal plants, 2007 Referee in the following International Journals: Journal of Planta Medica, 2005 Journal of Evidence Based Complementary and Alternative Medicine, 2006 International Journal of Radiation Biology, 2007

Apitherapy, Immunology