Microbial Parasitic and Fungal Immunology

Microbial Immunology expects studies examining responses to any microbial agent, including viruses, bacteria and parasites. The Microbiology, Microbial Pathogenesis and Immunology concentrate on the study of host-pathogen interactions at the molecular and cellular levels

May include abstracts focusing on:

  • Cellular Responses to Bacterial, Parasitic, and Fungal Pathogens
  • Immuno pathogenesis of Bacterial, Parasitic, and Fungal Infection
  • Innate Immunity Against Bacterial, Parasitic, and Fungal Pathogens
  • Mechanisms of Host Invasion, Evasion, and Resistance

Immunity to Malaria

Immunity to sporozoites injected by mosquite .Mediated by antibody that prevents infection of liver cells.Immunity to parasites in liver cells.Mediated by CD4+ and CD8+ T cells producing IFN-!Not lytic activity but IFN-! prevents replication of parasite Immunity to parasites in red blood cellsExponential growth stage and symptoms of disease.TH1 cells produce IL-2 and IFN-! (proinflammatory cytokines).M" activated and destroy infected RBCTH2 cells drive specific Ab production blocks invasion of new RBC Destroys infected RBCs through complement activation Enhances phagocytosis by M" through FcR Overproduction of TH1 cytokines

Important for parasite control

Produces life threatening complications of cerebral malaria, Anemia and other symptoms. Sequestration of parasites in the brain leads to the Production and release of proinflammatory cytokinesTH1 cytokines IFN-! IL-2, TNF, IL-1.Mediate the brain lesions and neurologic damage NO produced by cerebral endothelium interferes with Neurotransmission.

Immunity to Schistosomiasis

Correlative evidence: high IL-4, IL-5, and IgE individuals remain un-reinjected .High IFN-g in individuals who were reinvested. Disease is due to TH2-directed granulomatous response to worm egg antigens B cells proliferate and produce IL-10 IL-10 stops stimulation of APCs Down modulates the size of the granuloma

 

 

  • Immunity to Malaria
  • Important for parasite control
  • Immunity to Schistosomiasis

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2nd European Congress on Virology and Immunology

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International Conference on Immunology Research

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Microbial Parasitic and Fungal Immunology Conference Speakers

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