Cancer and Tumour Immunology

However, the system could even be able to mount an attack against the few tumour cells that are spared by the chemotherapeutic agent. there's an increased incidence of malignancies in immuno-deficient patients like AIDS patients who are susceptible to Kaposi sarcoma and transplant patients who are susceptible to Epstein Barr virus (EBV)-induced lymphoma. Tumor-specific antibodies and T lymphocytes. Hosts are often specifically immunized against various sorts of tumors demonstrating tumour antigens can elicit an immune reaction . A tumour that grows in an animal strain also will grow in another animal belonging to the same inbred strain obtained by repeated brother-sister mating’s. These animals express the same MHC molecule and are mentioned as syngeneic. However, most conventional animal populations are allogeneic and have various MHC haplotypes. Thus, a tumour transferred from one animal to a special animal belonging to an outbred strain is rejected thanks to the allo-MHC rather than the TSTA. A tumour transferred from an animal belonging to a minimum of one species a special">to a special animal belonging to a special species is rapidly rejected because the animals are xenogeneic.

  • Papova (papilloma, polyoma) viruses
  • Human T-lymphotropic viruses
  • Tumour-specific transplantation antigens
  • Tumour associated transplantation antigens
  • Bacillus Calmette-Guerin
  • Hepatitis B vaccine

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